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Home > Medical Specialties > Reproductive Endocrinology & Infertility > Clinic For Human Reproduction > Clinic For Human Reproduction

Clinic For Human Reproduction


The Clinic for Human Reproduction (CHR) within the Department of Obstetrics & Gynecology, National University Hospital (NUH) was set up to treat couples with fertility problems. It was the first clinic in Singapore to offer services for in-vitro fertilization (IVF) back in 1982 when it was situated in Kandang Kerbau Hospital. In 1985 when the Department of Obstetrics & Gynaecology moved to NUH, the fertility clinic was relocated as well and since then, the centre has been treating thousands of couples both locally and internationally for fertility problems.


The centre is a one-stop centre for a wide range of services dealing with the investigation and management of couples with infertility problems. With an emphasis on continual research and update, the centre is able to provide a comprehensive range of treatment methods for fertility problems.




Please click here to read the CHR Updates.

Range of Services

The fertility services offered by CHR include those for both males and females:

  • Women with fertility problems:
    - Ovulation problems
    - Blocked fallopian tubes
    - Endometriosis
    - Polycystic ovary syndrome
    - Miscellaneous problems including ovarian cysts, fibroids and a history of previous tubal sterilisation.
  • Men with fertility problems include low sperm count, low sperm motility or abnormality of the shapes of the sperm.
  • Couples with unexplained infertility, sexual problems and recurrent pregnancy loss.

Clinical Services

  • Correction of ovulatory problems (induction of ovulation)
  • Timing of ovulation
  • Intrauterine insemination (IUI)
  • In-vitro fertilization (IVF)
  • Intra-cytoplasmic sperm injection (ICSI)
  • Sperm, egg and embryo donation programmes
  • Micro-surgical epididymal sperm aspiration (MESA). This is a technique whereby sperm is collected from the epididymis in men with no sperm in their ejaculate to be used for IVF - ICSI.
  • Testicular sperm aspiration. A process whereby the sperm is collected from testicular biopsy to be used for IVF - ICSI.
  • Extended embryo culture. Arising from a better understanding of embryo culture techniques in an IVF programme, we are now able to culture our embryos to a later stage often up to a Day 5 blastocyst stage. We have shown that transferring blastocysts whenever available increases the pregnancy rate.
  • Laser assisted hatching. This process is used when couples have embryos with an excessively thick shell and hence the laser is use to help to facilitate the hatching process.



For the last 31 years, the centre has been assisting thousands of couples to conceive and many babies have been born as a result of our fertility programmes. Our IVF programme has been very successful and the summary of the results from 2000 - 2015 are shown in the table below.


Clinical Pregnancy Rates per Embryo Transfer in NUH: 2000 - 2015

Age (Years) %
Less than 30 42.4
30 – 34 38.4
35 – 39 28.4
40 and above 9.9
Average 29.8

Success rate of pregnancy for women above 45 is less than 1%.


Age and Fertility

It can be seen from the results that increasing age has a significant impact on the pregnancy rate and we therefore encourage patients with infertility problems to seek help early so that the fertility treatments will be more successful.


Please click here to find out more about ART Funding.


Please contact the Clinic For Human Reproduction at 1800 -CALL-CHR (1800 - 2255 247) for more information or to make an appointment, or email us at  chr@nuhs.edu.sg




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Further Information




Division of Reproductive Endocrinology & Infertility


Head of Division

Dr Stephen Chew


Senior Consultants

Prof P C Wong

 Dr Susan Logan



Dr Shakina Rauff


Associate Consultant

Dr Huang Zhong Wei



Chief Embryologist
Joyce Mathew



Elizabeth Ng

Elsa Sandy Kwe
Glynis Foong

Kay Thi Tun

Mary Nee

Phoebe Cheah

Preeja Sreedhar




Christine Kasono

Janice Tay

Jenniffey Ling

Jillian Policompio Acenas

Lang Chunyan

Maithili D/O Mathivannan 

Muhsinah Binti Abdul Aleem